RWJ-445167

• Description :

  RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.

• CAS Number :

  [226566-43-4]

• Product Name Alternative :

  3DP-10017

• UNSPSC :

  12352005

• Target :

  Factor Xa; Thrombin

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/RWJ-445167.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NCCONC(N)=N)CN1C(C)=CC=C(NS(=O)(C2=CC=CC(C)=C2)=O)C1=O

• Molecular Formula :

  C18H24N6O5S

• Molecular Weight :

  436.49

• References & Citations :

  [1]RWJ-445167, et al. Exploration of potential prodrugs of RWJ-445167, an oxyguanidine-based dual inhibitor of thrombin and factor Xa. Chem Biol Drug Des. 2006 Jul;68 (1) :29-36.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported