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RWJ-445167

CAT: 0804-HY-19373Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19373Size:1 Each
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Description
RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.
CAS Number
226566-43-4
Product Name Alternative
3DP-10017
UNSPSC
12352005
Target
Factor Xa; Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/RWJ-445167.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCONC(N)=N)CN1C(C)=CC=C(NS(=O)(C2=CC=CC(C)=C2)=O)C1=O
Molecular Formula
C18H24N6O5S
Molecular Weight
436.49
References & Citations
[1]RWJ-445167, et al. Exploration of potential prodrugs of RWJ-445167, an oxyguanidine-based dual inhibitor of thrombin and factor Xa. Chem Biol Drug Des. 2006 Jul;68 (1) :29-36.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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T12782-01RWJ-445167
A12154-50RWJ-445167 50mg
A12154-25RWJ-445167 25mg
A12154-100RWJ-445167 100mg
A12154-10RWJ-445167 10mg
A12154-5RWJ-445167 5mg
A12154-1RWJ-445167 1mg
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