K-Ras G12C-IN-2

• UNSPSC Description:

  K-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor.

• Target Antigen:

  Ras

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;MAPK/ERK Pathway

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/K-Ras-G12C-IN-2.html

• Purity:

  99.21

• Solubility:

  DMSO : ≥ 22 mg/mL

• Smiles:

  ClC1=C(C2CC2)C=C(NCC(N3CCN(C4CN(C(C=C)=O)C4)CC3)=O)C(O)=C1

• Molecular Weight:

  418.92

• References & Citations:

  [1]Pingda Ren, et al. Covalent inhibitors of kras g12c. WO2014152588A1

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1629267-75-9