K-Ras(G12C) inhibitor 9

• UNSPSC Description:

  K-Ras (G12C) inhibitor 9 is an allosteric inhibitor of the K-Ras (G12C)[1].

• Target Antigen:

  Ras

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/k-ras-g12c-inhibitor-9.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  C=CS(=O)(NC1CCN(C(CNC2=CC(I)=C(Cl)C=C2OC)=O)CC1)=O

• Molecular Weight:

  513.78

• References & Citations:

  [1]Ostrem JM, et al. K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. Nature. 2013 Nov 28;503(7477):548-51.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1469337-91-4