Iloperidone (hydrochloride)

CAT: 0804-HY-17410ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-17410ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Iloperidone hydrochloride (HP 873 hydrochloride) is a D2/5-HT2 receptor antagonist. Iloperidone hydrochloride is an atypical antipsychotic for the schizophrenia symptoms[1][2].
CAS Number
[1299470-39-5]
Product Name Alternative
HP 873 hydrochloride
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/iloperidone-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(OCCCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)C(OC)=C1)=O.Cl
Molecular Formula
C24H28ClFN2O4
Molecular Weight
462.94
References & Citations
[1]Kongsamut, S., et al., Iloperidone binding to human and rat dopamine and 5-HT receptors. Eur J Pharmacol, 1996. 317 (2-3) : p. 417-23.|[2]Sainati, S.M., et al., Safety, tolerability, and effect of food on the pharmacokinetics of iloperidone (HP 873), a potential atypical antipsychotic. J Clin Pharmacol, 1995. 35 (7) : p. 713-20.|[3]Albers, L.J., A. Musenga, and M.A. Raggi, Iloperidone: a new benzisoxazole atypical antipsychotic drug. Is it novel enough to impact the crowded atypical antipsychotic market? Expert Opin Investig Drugs, 2008. 17 (1) : p. 61-75.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
D1 Receptor; D2 Receptor; D3 Receptor; D4 Receptor; D5 Receptor; mLAG-3; MUC2; MUC3; α-1 microglobulin

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