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Iloperidone

CAT: 0804-HY-17410-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17410-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Iloperidone (HP 873) is a D2/5-HT2 receptor antagonist. Iloperidone is an atypical antipsychotic for the schizophrenia symptoms[1][2].
CAS Number
133454-47-4
Product Name Alternative
HP 873
UNSPSC
12352005
Hazard Statement
H301, H413
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/iloperidone.html
Purity
99.93
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(C1=CC=C(OCCCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)C(OC)=C1)=O
Molecular Formula
C24H27FN2O4
Molecular Weight
426.48
Precautions
H301, H413
References & Citations
[1]Kongsamut, S., et al., Iloperidone binding to human and rat dopamine and 5-HT receptors. Eur J Pharmacol, 1996. 317 (2-3) : p. 417-23.|[2]Sainati, S.M., et al., Safety, tolerability, and effect of food on the pharmacokinetics of iloperidone (HP 873), a potential atypical antipsychotic. J Clin Pharmacol, 1995. 35 (7) : p. 713-20.|[3]Albers, L.J., A. Musenga, and M.A. Raggi, Iloperidone: a new benzisoxazole atypical antipsychotic drug. Is it novel enough to impact the crowded atypical antipsychotic market? Expert Opin Investig Drugs, 2008. 17 (1) : p. 61-75.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
D1 Receptor; D2 Receptor; D3 Receptor; D4 Receptor; D5 Receptor; mLAG-3; MUC2; MUC3; α-1 microglobulin

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A5399-5.1Iloperidone

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