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Lansoprazole (sodium)

CAT: 0804-HY-13662ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-13662ASize:1 Each
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Description
Lansoprazole sodium (AG 1749 sodium) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole sodium (AG 1749 sodium) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [1][2].
CAS Number
226904-00-3
Product Name Alternative
AG-1749 (sodium)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bacterial; Phospholipase; Proton Pump
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lansoprazole-sodium.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=NC2=CC=CC=C2[N-]1)CC3=NC=CC(OCC(F)(F)F)=C3C.[Na+]
Molecular Formula
C16H13F3N3NaO2S
Molecular Weight
391.34
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Kokufu, T., et al., Effects of lansoprazole on pharmacokinetics and metabolism of theophylline. Eur J Clin Pharmacol, 1995. 48 (5) : p. 391-5.|[2]Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35 (1) :1322-1330.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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