Duocarmycin analog-1

• Description:

  Duocarmycin analog-1 is an analog of Duocarmycin, and used as an DNA alkylator and ADC cytotoxin[1].

• UNSPSC:

  12352203

• Target:

  ADC Payload; DNA Alkylator/Crosslinker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/duocarmycin-analog.html

• Purity:

  95.85

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (OC (C) (C) C) NC1=CC=C (C (NC2=CC3=C (NC (C (N4C[C@@H] (CCl) C5=C4C=C (O) C6=CC=CC=C56) =O) =C3) C=C2) =O) C=C1

• Molecular Formula:

  C34H31ClN4O5

• Molecular Weight:

  611.09

• References & Citations:

  [1]Boger, Dale L. CBI ANALOGUES OF CC-1065 AND THE DUOCARMYCINS. WO2003022806A2

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Duocarmycins

• CAS Number:

  372954-15-9