Duocarmycin analog-1

• Description :

  Duocarmycin analog-1 is an analog of Duocarmycin, and used as an DNA alkylator and ADC cytotoxin[1].

• CAS Number :

  [372954-15-9]

• UNSPSC :

  12352203

• Target :

  ADC Payload; DNA Alkylator/Crosslinker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/duocarmycin-analog.html

• Purity :

  95.85

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OC(C)(C)C)NC1=CC=C(C(NC2=CC3=C(NC(C(N4C[C@@H](CCl)C5=C4C=C(O)C6=CC=CC=C56)=O)=C3)C=C2)=O)C=C1

• Molecular Formula :

  C34H31ClN4O5

• Molecular Weight :

  611.09

• References & Citations :

  [1]Boger, Dale L. CBI ANALOGUES OF CC-1065 AND THE DUOCARMYCINS. WO2003022806A2

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Duocarmycins