Bortezomib analog 1
CAT:
804-HY-169158
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Bortezomib analog 1
- UNSPSC Description: Bortezomib analog 1 is an analog of Bortezomib (HY-10227). Bortezomib analog 1 and can be used to synthesize PROTAC 20S proteasome subunit β5 degrader 1 (HY-169134)[1].
- Target Antigen: Ligands for Target Protein for PROTAC
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/bortezomib-analog-1.html
- Smiles: CC1(C)[C@H]2[C@]3(C(OB([C@@H](NC([C@H](CC4=CC=CC=C4)NC(C5=CC=C(C(OC(C)(C)C)=O)C=C5)=O)=O)CC(C)C)O3)C[C@@H]1C2)C
- Molecular Weight: 616.60
- References & Citations: [1]Wang S, et al. Discovery of novel 20S proteasome subunit β5 PROTAC degraders as potential therapeutics for pharyngeal carcinoma and Bortezomib-resistant multiple myeloma. Bioorg Chem. 2024 Sep 3;153:107801.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported