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TG101209 analog 1

CAT: 0804-HY-172089-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-172089-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TG101209 analog 1 (Compound 8h) is an inhibitor for BUB1B with an IC50 of 10.36 μM. TG101209 analog 1 exhibits cytotoxicity (IC50 for Caki-1 is 1.347 μM), induce necrosis and apoptosis[1].
UNSPSC
12352005
Target
Apoptosis
Related Pathways
Apoptosis
Field of Research
Cancer
Purity
98.27
Solubility
DMSO : 350 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=CC(NC2=NC(NC3=CC(OC)=C(OC)C(OC)=C3)=NC=C2C)=C1)(NC(C)(C)C)=O
Molecular Formula
C24H31N5O5S
Molecular Weight
501.60
References & Citations
[1]El Hafi M, et al., Synthesis and biological assessment of BUB1B inhibitors for the treatment of clear cell renal cell carcinoma. Eur J Med Chem. 2025 Jan 9;285:117247.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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