DMAC-PDB

• Description:

  DMAC-PDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

• UNSPSC:

  12352203

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dmac-pdb.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (O) CCCSSC1=NC=C (C (N (C) C) =O) C=C1

• Molecular Formula:

  C12H16N2O3S2

• Molecular Weight:

  300.40

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Wayne Charles Widdison, et al. Cross-linkers with high reactivity and solubility and their use in the preparation of conjugates for targeted delivery of small molecule drugs. WO2004016801A2

• Shipping Conditions:

  Room temperature

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Cleavable Linker; Disulfide Cleavable Linker

• CAS Number:

  663599-04-0