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DMAC-SPP

CAT: 0013-GTR19225639-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19225639-01Size:100 mg
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Description
DMAC-SPP is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) for targeted cancer therapy. Its design enables controlled drug release in both in vitro and in vivo research settings, facilitating the study of ADC efficacy and payload delivery mechanisms.
CAS Number
663599-10-8
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (ON1C (=O) CCC1=O) CCC (SSC=2C=CN=CC2C (=O) N (C) C) C
Molecular Formula
C17H21N3O5S2
Molecular Weight
411.5
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2,5-Dioxopyrrolidin-1-yl 4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoate
CAS Number663599-10-8
PubChem CID118797505
IUPAC Name(2,5-dioxopyrrolidin-1-yl) 4-[[3-(dimethylcarbamoyl)-4-pyridinyl]disulfanyl]pentanoate
Molecular FormulaC17H21N3O5S2
Molecular Weight411.5
XLogP0.6
Topological Polar Surface Area147
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Heavy Atom Count27
Formal Charge0
Complexity571
SMILES
CC(CCC(=O)ON1C(=O)CCC1=O)SSC2=C(C=NC=C2)C(=O)N(C)C
InChI
InChI=1S/C17H21N3O5S2/c1-11(4-7-16(23)25-20-14(21)5-6-15(20)22)26-27-13-8-9-18-10-12(13)17(24)19(2)3/h8-11H,4-7H2,1-3H3
InChIKey
AFGUQHOCEUTKEQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2,5-Dioxopyrrolidin-1-yl 4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoate
CAS: 663599-10-8
CID: 118797505
Formula: C17H21N3O5S2
MW: 411.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight411.5
XLogP30.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Exact Mass411.09226313
Monoisotopic Mass411.09226313
Topological Polar Surface Area147 Ų
Heavy Atom Count27
Formal Charge0
Complexity571
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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