(R) -CSN5i-3

• Description:

  (R) -CSN5i-3 is the (R) -enantiomer of CSN5i-3. CSN5i-3 is a potent, selective and orally available inhibitor of CSN5[1].

• UNSPSC:

  12352005

• Target:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/r-csn5i-3.html

• Purity:

  99.87

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC(C(F)F)=NN1C(C)C)NC2=CC(C3=CC=CC=C3)=C([C@H]4N5C(CCC[C@H]4O)=CN=C5)C=C2

• Molecular Formula:

  C28H29F2N5O2

• Molecular Weight:

  505.56

• References & Citations:

  [1]Schlierf A, et al. Targeted inhibition of the COP9 signalosome for treatment of cancer. Nat Commun. 2016 Oct 24;7:13166.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2863607-74-1]