(R)-MALT1-IN-3
CAT:
804-HY-143422A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(R)-MALT1-IN-3
- CAS Number: 2504229-61-0
- UNSPSC Description: (R)-MALT1-IN-3 (compound 121) is a potent MALT1 protease inhibitor with an IC50 of 20 nM. (R)-MALT1-IN-3 has IC50 of 60 nM, 40 nM for human IL6/IL10 in OCI-LY3 cells, respectively[1].
- Target Antigen: MALT1
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease;NF-κB
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/r-malt1-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: CO[C@H](C1CC1)C2=C(C#N)C(C)=NC=C2NC(NC3=CN=C(N4N=CC=N4)C(C(F)(F)F)=C3)=O
- Molecular Weight: 472.42
- References & Citations: [1]Johannes Wilhelmus J Thuring, et al. Pyridine rings containing derivatives as malt1 inhibitors
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported