CSN5i-3 B

• Description:

  CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5. It inhibits CSN-catalyzed Cul1 deneddylation with an IC50 value of 5.8 nM. CSN5i-3 has a killing effect on a variety of cancer cells and can be used as an anticancer drug.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  505.56

• Molecular Formula:

  C28H29F2N5O2

• Notes:

  Research use only, not for human use.

• Receptor:

  Apoptosis

• CAS Number:

  2375740-98-8