(R)-ICMT-IN-3

• UNSPSC Description:

  (R)-ICMT-IN-3 (compound ent 2-27) is an inhibitor of ICMT (IC50=0.01 μM)[1].

• Target Antigen:

  ICMT

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/r-icmt-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(OCC1)(C)C[C@@]1(C2=CC=CC=C2)CCNC3=CC=C(OC)C=C3

• Molecular Weight:

  339.47

• References & Citations:

  [1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT). J Med Chem. 2011 Jul 28;54(14):5031-47.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported