TP-5801 (TFA)
CAT:
804-HY-147316A-01
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TP-5801 (TFA)
- UNSPSC Description: TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor (IC50=1.40 nM), and shows anti-tumor activity[1].
- Target Antigen: STAT
- Type: Reference compound
- Related Pathways: JAK/STAT Signaling;Stem Cell/Wnt
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tp-5801-tfa.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: OC(C(F)(F)F)=O.CN1CCN(C2=C(C)C=C(NC3=NC=C(Br)C(NC4=CC=CN=C4N(C)C)=N3)C(OC)=C2)CC1
- Molecular Weight: 641.48
- References & Citations: [1]Tsz-Yin Chan, et al. TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Nat Commun. 2021 Sep 9;12(1):5337.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported