TP-TRFS

• Description:

  TP-TRFS is a highly selective and the first two-photon fluorescent probe of thioredoxin reductase (TrxR) [1].

• UNSPSC:

  12352005

• Target:

  TrxR

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/tp-trfs.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC (C1=CC=C2C=C (C=CC2=C1) NC (OC3CSSC3) =O) =O

• Molecular Formula:

  C16H15NO3S2

• Molecular Weight:

  333.43

• References & Citations:

  [1]Jintao Zhao, et al. Loss of thioredoxin reductase function in a mouse stroke model disclosed by a two-photon fluorescent probe. Chem Commun (Camb) . 2020 Nov 12;56 (90) :14075-14078.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2937819-61-7