PD-1-IN-17 (TFA)

CAT: 0804-HY-101097ASize: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-101097ASize:1 Each

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Description

PD-1-IN-17 TFA is a programmed cell death-1 (PD-1) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM[1].

UNSPSC

12352005

Target

PD-1/PD-L1

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pd-1-in-17-tfa.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H](C(O)=O)NC(N[C@H](C1=NN=C([C@@H](N)[C@H](O)C)O1)CCC(N)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C15H23F3N6O9

Molecular Weight

488.37

References & Citations

[1]Pottayil Govindan Nair Sasikumar, et al. 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives as immunomodulators. WO2015033301A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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T63256-01	PD-1-IN-17 TFA
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