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KCNH4 rabbit pAb

CAT: 0855-ES15347-01Size: 50 µLDry Ice: NoHazardous: No
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Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system. [provided by RefSeq, Jul 2008]
Description
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system. [provided by RefSeq, Jul 2008],
UniProt
Q9UQ05
Swiss Prot
Q9UQ05
Reactivity
Human; Rat
Immunogen
Synthesized peptide derived from human KCNH4.AA range:180-250
Target
KCNH4
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Membrane; Multi-pass membrane protein.
Gene ID (Human)
23415

UniProtKB · Q9UQ05

Voltage-gated delayed rectifier potassium channel KCNH4

KCNH4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UQ05
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KCNH4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

PTM

Glycoprotein

Molecular function

Ion channelPotassium channelVoltage-gated channel

Biological process

Ion transportPotassium transportTransport

Cellular component

Membrane

Ligand

Potassium

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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