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KCNH3 rabbit pAb

CAT: 0855-ES5342-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5342-01Size:50 µL
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Background
The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Description
The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015],
UniProt
Q9ULD8
Swiss Prot
Q9ULD8
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from KCNH3 . at AA range: 470-550
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
120kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
120kD
Fragment
IgG
Subcellular Location
Membrane; Multi-pass membrane protein.
Other Product Names
KCNH3; KIAA1282; Potassium voltage-gated channel subfamily H member 3; Brain-specific eag-like channel 1; BEC1; Ether-a-go-go-like potassium channel 2; ELK channel 2; ELK2; Voltage-gated potassium channel subunit Kv12.2
Gene ID (Human)
23416

UniProtKB · Q9ULD8

Voltage-gated inwardly rectifying potassium channel KCNH3

KCNH3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9ULD8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KCNH3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9UQ06
Protein keywords

Cellular component

Cell membraneMembrane

PTM

Glycoprotein

Molecular function

Ion channelPotassium channelVoltage-gated channel

Biological process

Ion transportPotassium transportTransport

Ligand

Potassium

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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