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MK-447

CAT: 0804-HY-100297Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-100297Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MK-447 is a free radical scavenger, also a nonsteroidal antiinflammatory agent, and enhances the formation of the endoperoxide, PGH2, and other prostaglandins.
CAS Number
58456-91-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/MK-447.html
Solubility
10 mM in DMSO
Smiles
OC1=C(I)C=C(C(C)(C)C)C=C1CN
Molecular Formula
C11H16INO
Molecular Weight
305.16
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Shriver DA, et al. The gastric antisecretory and antiulcer activity of MK-447, an enhancer of prostaglandin synthesis. Life Sci. 1980 Dec 22-29;27 (25-26) :2483-7.|[2]Harada Y, et al. Acceleration of endogeneous PGI2 generation from isolated rat aortae by MK-447. Jpn J Pharmacol. 1981 Oct;31 (5) :845-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IP

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