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FK-448 Free base

CAT: 0804-HY-100193Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-100193Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM.
CAS Number
85858-76-0
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/FK-448_Free_base.html
Solubility
10 mM in DMSO
Smiles
O=C(C1CCCC2=C1C=CC=C2)OC3=CC=C(C(N4CCN(C(C)C)CC4)=O)C=C3
Molecular Formula
C25H30N2O3
Molecular Weight
406.52
References & Citations
[1]Fujii S, et al. New synthetic inhibitors of chymotrypsin. J Biochem. 1984 Feb;95 (2) :319-22.|[2]Fujii S, et al. Promoting effect of the new chymotrypsin inhibitor FK-448 on the intestinal absorption of insulin in rats and dogs. J Pharm Pharmacol. 1985 Aug;37 (8) :545-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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