CX-157

• Description :

  CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL.

• UNSPSC :

  12352005

• Target :

  Monoamine Oxidase

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/CX-157.html

• Solubility :

  10 mM in DMSO

• Smiles :

  FC(F)(F)COC1=CC(OC2=CC(F)=CC=C2S3(=O)=O)=C3C=C1

• Molecular Formula :

  C14H8F4O4S

• Molecular Weight :

  348.27

• References & Citations :

  [1]Fowler JS, et al. Reversible inhibitors of monoamine oxidase-A (RIMAs) : robust, reversible inhibition of human brain MAO-A by CX157. Neuropsychopharmacology. 2010 Feb;35 (3) :623-31.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [205187-53-7]