BPC 157

• Description :

  BPC 157 is the 15-amino acide fragment of gastric peptide BPC. BPC 157 exhibits wound healing promoting and neuroprotective activity. BPC 157 maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 ameliorates specific (over) stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems[1][2][3].

• UNSPSC :

  12352209

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  FAK; JAK

• Type :

  Peptides

• Related Pathways :

  Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/bpc-157.html

• Purity :

  99.86

• Solubility :

  DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

• Smiles :

  O=C([C@H]1N(CCC1)C([C@H](CCC(O)=O)NC(CN)=O)=O)N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(NCC(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C62H98N16O22

• Molecular Weight :

  1419.54

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Sikiric P, et al. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Curr Pharm Des. 2011;17 (16) :1612-1632.|[2]Klicek R, et al. Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability. J Physiol Pharmacol. 2013;64 (5) :597-612.|[3]Desgagné M, et al., Development of Macrocyclic Neurotensin Receptor Type 2 (NTS2) Opioid-Free Analgesics. Angew Chem Int Ed Engl. 2024 Nov 18;63 (47) :e202405941.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [137525-51-0]