AFX Colorimetric Cell-Based ELISA

CAT: 0519-EKC1926Size: 1 Kit - Containing One 96 Well Plate & All Necessary ReagentsDry Ice: NoHazardous: No
CAT#:0519-EKC1926Size:1 Kit - Containing One 96 Well Plate & All Necessary Reagents
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
The AFX Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor AFX protein expression profile in cells. The kit can be used for measuring the relative amounts of AFX in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on AFX.
Synonyms
Forkhead box protein O4; Fork head domain transcription factor AFX1; FOXO4; AFX, AFX1, MLLT7
Gene Name
FOXO4
UniProt
P98177
Reactivity
Human, Mouse
Tissue Specificity
Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform zeta is most abundant in the liver, kidney, and pancreas.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Molecular Weight
53684 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Forkhead box protein O4
Subcellular Location
Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.

Related Products

CatalogName
EKC1627TRIM24 Colorimetric Cell-Based ELISA
EKC1670FES Colorimetric Cell-Based ELISA
EKC1643Dyskerin Colorimetric Cell-Based ELISA
EKC1630Clock Colorimetric Cell-Based ELISA
EKC1759COPS2 Colorimetric Cell-Based ELISA
EKC1885ZNF785 Colorimetric Cell-Based ELISA
EKC1795JIP2 Colorimetric Cell-Based ELISA
EKC1824TSN Colorimetric Cell-Based ELISA
EKC1698MARK3 Colorimetric Cell-Based ELISA
EKC1774HSF2 Colorimetric Cell-Based ELISA

Alternative Products

CatalogName
MBS9500957-01CBP Colorimetric Cell-Based ELISA Kit
MBS9500933-01PGBD1 Colorimetric Cell-Based ELISA Kit
MBS9500931-01IP3KC Colorimetric Cell-Based ELISA Kit
MBS9500927-01TF3B Colorimetric Cell-Based ELISA Kit
MBS9500925-01FOXJ1 Colorimetric Cell-Based ELISA Kit
MBS9500924-01COPS5 Colorimetric Cell-Based ELISA Kit
MBS9500916-01GRK7 Colorimetric Cell-Based ELISA Kit
MBS9500172-01DAPP1 Colorimetric Cell-Based ELISA Kit
MBS9500909-01IPMK Colorimetric Cell-Based ELISA Kit
MBS9500907-01ZNF397 Colorimetric Cell-Based ELISA Kit

Popular Products