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SMG7 Colorimetric Cell-Based ELISA

CAT: 0519-EKC1888Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1888Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The SMG7 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor SMG7 protein expression profile in cells. The kit can be used for measuring the relative amounts of SMG7 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on SMG7.
Synonyms
Protein SMG7; EST1-like protein C; SMG-7 homolog; hSMG-7; SMG7; C1orf16, EST1C, KIAA0250
Gene Name
SMG7
UniProt
Q92540
Reactivity
Human
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.
Molecular Weight
127282 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Protein SMG7
Subcellular Location
Cytoplasm. Nucleus. Predominantly cytoplasmic, and nuclear. Shuttles between nucleus and cytoplasm.

UniProtKB · Q92540

Nonsense-mediated mRNA decay factor SMG7

SMG7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92540
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SMG7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DRB2, E9PCI0, E9PEH2, Q5T1Q0, Q6PIE0, Q7Z7H9, Q8IXC1, Q8IXC2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Biological process

Nonsense-mediated mRNA decay

Domain

RepeatTPR repeat

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