RegisterLogin

MAP4K6 Colorimetric Cell-Based ELISA

CAT: 519-EKC1871Size: 1 Kit - Containing One 96 Well Plate & All Necessary ReagentsDry Ice: NoHazardous: No
1 Kit - Containing One 96 Well Plate & All Necessary ReagentsSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
The MAP4K6 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MAP4K6 protein expression profile in cells. The kit can be used for measuring the relative amounts of MAP4K6 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MAP4K6.
Synonyms
Misshapen-like kinase 1;2.7.11.1; GCK family kinase MiNK; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; Misshapen/NIK-related kinase; Mitogen-activated protein kinase kinase kinase kinase 6; MINK1 ; B55, MAP4K6 , MINK , YSK2, ZC3
Gene Name
MINK1 B55, MAP4K6 , MINK , YSK2, ZC3
UniProt
Q8N4C8
Reactivity
Human, Mouse
Tissue Specificity
Expressed in the brain, isoform 2 is more abundant than isoform 1. Isoform 3 is ubiquitously expressed. Isoform 1 is most abundant in the skeletal muscle. Isoform 4 is ubiquitously expressed with relative high levels in brain, skeletal muscle, pancreas and testis.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.
Molecular Weight
149822 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Misshapen-like kinase 1
Subcellular Location
Cytoplasm. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, axon. Cell projection, dendrite.

Related Products

CatalogName
EKC1741MAP2K6 Colorimetric Cell-Based ELISA
EKC1835MAPK3 Colorimetric Cell-Based ELISA
EKC1348MAP3K8 Colorimetric Cell-Based ELISA Kit
EKC1347MAP3K7 Colorimetric Cell-Based ELISA Kit
EKC1346MAP2K7 Colorimetric Cell-Based ELISA Kit
EKC1702P42 MAPK Colorimetric Cell-Based ELISA
EKC1783MN1 Colorimetric Cell-Based ELISA
EKC1716ACV1B Colorimetric Cell-Based ELISA
EKC1793CDK5R2 Colorimetric Cell-Based ELISA
EKC1624BACH1 Colorimetric Cell-Based ELISA

Alternative Products

CatalogName
MBS9500904-01MAP4K6 Colorimetric Cell-Based ELISA Kit
OKAG01394MAP4K6 Colorimetric Cell-Based ELISA Kit (OKAG01394)
CB6079MAP4K6 Cell-Based ELISA
MBS9500003-01OCT1 Colorimetric Cell-Based ELISA Kit
MBS9500013-01ACC1 Colorimetric Cell-Based ELISA Kit
MBS9500022-01AIRE Colorimetric Cell-Based ELISA Kit
MBS9500026-01ALK Colorimetric Cell-Based ELISA Kit
MBS9500034-01AOS1 Colorimetric Cell-Based ELISA Kit
MBS9500039-01A-RAF Colorimetric Cell-Based ELISA Kit
MBS9500042-01ASK1 Colorimetric Cell-Based ELISA Kit

Popular Products