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NR1I3 Colorimetric Cell-Based ELISA

CAT: 0519-EKC1813Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1813Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The NR1I3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor NR1I3 protein expression profile in cells. The kit can be used for measuring the relative amounts of NR1I3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on NR1I3.
Synonyms
Nuclear receptor subfamily 1 group I member 3; Constitutive activator of retinoid response; Constitutive active response; Constitutive androstane receptor; CAR; Orphan nuclear receptor MB67; NR1I3; CAR
Gene Name
NR1I3
UniProt
Q14994
Reactivity
Human
Tissue Specificity
Predominantly expressed in liver.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
Molecular Weight
39942 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Nuclear receptor subfamily 1 group I member 3
Subcellular Location
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Recruited to the cytoplasm by DNAJC7.

UniProtKB · Q14994

Nuclear receptor subfamily 1 group I member 3

NR1I3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14994
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NR1I3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
E9PB75, E9PC13, E9PDU3, E9PGH6, E9PH10, E9PHC8, E9PHN4, F1D8Q0, F1D8Q1, Q0VAC9, Q4U0F0, Q5VTW5, Q5VTW6, Q6GZ68, Q6GZ76, Q6GZ77, Q6GZ78, Q6GZ79, Q6GZ82, Q6GZ83, Q6GZ84, Q6GZ85, Q6GZ87, Q6GZ89
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDNA-bindingReceptor

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmCytoskeletonNucleus

Ligand

Metal-bindingZinc

PTM

Phosphoprotein

Biological process

TranscriptionTranscription regulation

Domain

Zinc-finger

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