NR1I3 Colorimetric Cell-Based ELISA

• Description:

  The NR1I3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor NR1I3 protein expression profile in cells. The kit can be used for measuring the relative amounts of NR1I3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on NR1I3.

• Synonyms:

  Nuclear receptor subfamily 1 group I member 3; Constitutive activator of retinoid response; Constitutive active response; Constitutive androstane receptor; CAR; Orphan nuclear receptor MB67; NR1I3; CAR

• Gene Name:

  NR1I3

• UniProt:

  Q14994

• Reactivity:

  Human

• Tissue Specificity:

  Predominantly expressed in liver.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.

• Molecular Weight:

  39942 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Nuclear receptor subfamily 1 group I member 3

• Subcellular Location:

  Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Recruited to the cytoplasm by DNAJC7.