SERC3 Colorimetric Cell-Based ELISA

• Description:

  The SERC3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor SERC3 protein expression profile in cells. The kit can be used for measuring the relative amounts of SERC3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on SERC3.

• Synonyms:

  Serine incorporator 3; Tumor differentially expressed protein 1 ; SERINC3; DIFF33, TDE1 ; SBBI99

• Gene Name:

  SERINC3SBBI99

• UniProt:

  Q13530

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734) .

• Molecular Weight:

  52580 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Serine incorporator 3

• Subcellular Location:

  Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.