LAT3 Colorimetric Cell-Based ELISA

• Description:

  The LAT3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor LAT3 protein expression profile in cells. The kit can be used for measuring the relative amounts of LAT3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on LAT3.

• Synonyms:

  Large neutral amino acids transporter small subunit 3; L-type amino acid transporter 3; Prostate cancer overexpressed gene 1 protein; Solute carrier family 43 member 1; SLC43A1 ; LAT3 , PB39 , POV1

• Gene Name:

  SLC43A1 LAT3 , PB39 , POV1

• UniProt:

  O75387

• Reactivity:

  Human

• Tissue Specificity:

  In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.

• Molecular Weight:

  61477 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Large neutral amino acids transporter small subunit 3

• Subcellular Location:

  Membrane; Multi-pass membrane protein.