TOP2A Colorimetric Cell-Based ELISA Kit

• Description:

  The TOP2A Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TOP2A protein expression profile in cells. The kit can be used for measuring the relative amounts of TOP2A in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TOP2A.

• Synonyms:

  DNA topoisomerase 2-alpha;5.99.1.3; DNA topoisomerase II, alpha isozyme; TOP2A; TOP2

• Gene Name:

  TOP2A

• UniProt:

  P11388

• Reactivity:

  Human

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) .

• Molecular Weight:

  174385 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  DNA topoisomerase 2-alpha

• Subcellular Location:

  Cytoplasm. Nucleus, nucleoplasm. Generally located in the nucleoplasm.