TOP2A (Phospho-Thr1343) Colorimetric Cell-Based ELISA Kit

• Description:

  The TOP2A (Phospho-Thr1343) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TOP2A (Phospho-Thr1343) protein expression profile in cells. The kit can be used for measuring the relative amounts of TOP2A (Phospho-Thr1343) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TOP2A (Phospho-Thr1343) .

• Synonyms:

  DNA topoisomerase 2-alpha;5.99.1.3; DNA topoisomerase II, alpha isozyme; TOP2A; TOP2

• Gene Name:

  TOP2A

• UniProt:

  P11388

• Reactivity:

  Human

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) .

• Molecular Weight:

  174385 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  DNA topoisomerase 2-alpha

• Subcellular Location:

  Cytoplasm. Nucleus, nucleoplasm. Generally located in the nucleoplasm.