SNAP25 Colorimetric Cell-Based ELISA Kit

• Description:

  The SNAP25 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor SNAP25 protein expression profile in cells. The kit can be used for measuring the relative amounts of SNAP25 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on SNAP25.

• Synonyms:

  Synaptosomal-associated protein 25; SNAP-25; Super protein; SUP; Synaptosomal-associated 25 kDa protein; SNAP25; SNAP

• Gene Name:

  SNAP25

• UniProt:

  P60880

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  T-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.

• Molecular Weight:

  23315 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Synaptosomal-associated protein 25

• Subcellular Location:

  Cytoplasm, perinuclear region. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. Colocalizes with KCNB1 at the cell membrane.