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HBP1 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1258Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1258Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The HBP1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor HBP1 protein expression profile in cells. The kit can be used for measuring the relative amounts of HBP1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on HBP1.
Synonyms
HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1; HBP1
Gene Name
HBP1
UniProt
O60381
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.
Molecular Weight
57645 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
HMG box-containing protein 1
Subcellular Location
Nucleus.

UniProtKB · O60381

HMG box-containing protein 1

HBP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60381
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HBP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B3KVB7, Q8TBM1, Q8TE93, Q96AJ2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

DNA-bindingRepressor

Cellular component

Nucleus

Biological process

TranscriptionTranscription regulationWnt signaling pathway

PTM

Ubl conjugation

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