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GluR5 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1244Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1244Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The GluR5 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GluR5 protein expression profile in cells. The kit can be used for measuring the relative amounts of GluR5 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GluR5.
Synonyms
Glutamate receptor ionotropic kainate 1; Glutamate receptor 5; GluR-5; GluR5; Excitatory amino acid receptor 3; EAA3; GRIK1
Gene Name
GRIK1
UniProt
P39086
Reactivity
Human, Mouse, Rat
Tissue Specificity
Most abundant in the cerebellum and the suprachiasmatic nuclei (SCN) of the hypothalamus.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
Molecular Weight
103981 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Glutamate receptor ionotropic, kainate 1
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

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