Products for Research Use Only
RegisterLogin

GATA4 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1237Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0519-EKC1237Size:1 Kit, containing one 96 Well Plate and all necessary reagents
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The GATA4 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GATA4 protein expression profile in cells. The kit can be used for measuring the relative amounts of GATA4 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GATA4.
Synonyms
DNA binding protein GATA-GT2; GAT4; GATA binding factor-4; GATA-4; Transcription factor GATA-4
Gene Name
GATA4
UniProt
P43694
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169, PubMed:27984724) . In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (PubMed:27984724) . Involved in bone morphogenetic protein (BMP) -mediated induction of cardiac- specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity) . Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity) . Promotes cardiac myocyte enlargement (PubMed:20081228) . Required during testicular development (PubMed:21220346) . May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase (PubMed:15734735) .
Molecular Weight
44565 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Transcription factor GATA-4
Subcellular Location
Nucleus.

UniProtKB · P43694

Transcription factor GATA-4

GATA4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P43694
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GATA4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B7ZKX0, B7ZKZ4, Q3MJ45, Q5IFM8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Disease

Atrial septal defectCardiomyopathyDisease variant

Ligand

Metal-bindingZinc

PTM

Methylation

Cellular component

Nucleus

Domain

RepeatZinc-finger

Biological process

TranscriptionTranscription regulation

Related Products

CatalogName
EKC2259GATA4 (Phospho-Ser262) Colorimetric Cell-Based ELISA Kit
EKC1236GATA1 Colorimetric Cell-Based ELISA Kit
EKC1238GATA6 Colorimetric Cell-Based ELISA Kit
EKC1359MEF2A Colorimetric Cell-Based ELISA Kit
EKC1455PHCA Colorimetric Cell-Based ELISA Kit
EKC1415Osteopontin Colorimetric Cell-Based ELISA Kit
EKC1373MKP1 Colorimetric Cell-Based ELISA Kit
EKC1112Chk1 Colorimetric Cell-Based ELISA Kit
EKC1526Smad1 Colorimetric Cell-Based ELISA Kit
EKC1555Synaptophysin Colorimetric Cell-Based ELISA Kit

Alternative Products

CatalogName
MBS9500250-01GATA4 Colorimetric Cell-Based ELISA Kit
OKAG00739GATA4 Colorimetric Cell-Based ELISA Kit (OKAG00739)
MBS9501301-01Phospho-GATA4 (Ser262) Colorimetric Cell-Based ELISA Kit
OKAG01791Phospho-GATA4 (Ser262) Colorimetric Cell-Based ELISA Kit (OKAG01791)
CB5290GATA4 Cell-Based ELISA Kit
CBP1375Phospho-GATA4 (Ser262) Cell-Based ELISA Kit
MBS9500271-01HBP1 Colorimetric Cell-Based ELISA Kit
MBS9500106-01CD5 Colorimetric Cell-Based ELISA Kit
MBS9500261-01GR Colorimetric Cell-Based ELISA Kit
MBS9500259-01GLUT3 Colorimetric Cell-Based ELISA Kit

Popular Products