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Galectin 3 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1233Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1233Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Galectin 3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Galectin 3 protein expression profile in cells. The kit can be used for measuring the relative amounts of Galectin 3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Galectin 3.
Synonyms
35 kDa lectin; CBP 35; Carbohydrate binding protein 35; GALBP; Galactose-specific lectin 3; Galactoside-binding protein; IgE-binding protein; L-31; L-34 galactoside-binding lectin; LEG3; LGALS3; Laminin-binding protein; Lectin L-29; MAC-2 antigen; MAC2
Gene Name
LGALS3
UniProt
P17931
Reactivity
Human, Mouse, Rat
Tissue Specificity
A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity) . In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Molecular Weight
26152 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Galectin-3
Subcellular Location
Cytoplasm. Nucleus. Secreted. Secreted by a non-classical secretory pathway and associates with the cell surface.

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