MGluR2/3 Colorimetric Cell-Based ELISA Kit

• Description:

  The mGluR2/3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor mGluR2/3 protein expression profile in cells. The kit can be used for measuring the relative amounts of mGluR2/3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on mGluR2/3.

• Synonyms:

  GPRC1C; GRM3; MGR3; Metabotropic glutamate receptor 3 precursor; glutamate receptor metabotropic type 3

• Gene Name:

  GRM2

• UniProt:

  Q14416

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Detected in brain cortex (at protein level) . Widely expressed in different regions of the adult brain as well as in fetal brain.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

• Molecular Weight:

  95568 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Metabotropic glutamate receptor 2

• Subcellular Location:

  Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite.