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ERK3 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1200Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1200Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The ERK3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ERK3 protein expression profile in cells. The kit can be used for measuring the relative amounts of ERK3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ERK3.
Synonyms
ERK-3; ERK3; Extracellular signal- regulated kinase 3; MAP kinase isoform p97; MAPK6; MK06; Mitogen-activated protein kinase 6; PRKM4; PRKM6; kinase ERK3; p55-MAPK; p97-MAPK
Gene Name
MAPK6
UniProt
Q16659
Reactivity
Human, Mouse, Rat
Tissue Specificity
Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity) .
Molecular Weight
82681 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Mitogen-activated protein kinase 6
Subcellular Location
Cytoplasm. Nucleus. Translocates to the cytoplasm following interaction with MAPKAPK5.

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