DAPP1 (Phospho-Tyr139) Colorimetric Cell-Based ELISA Kit

• Description:

  The DAPP1 (Phospho-Tyr139) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor DAPP1 (Phospho-Tyr139) protein expression profile in cells. The kit can be used for measuring the relative amounts of DAPP1 (Phospho-Tyr139) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on DAPP1 (Phospho-Tyr139) .

• Synonyms:

  3' phosphoinositide-interacting SH2 domain containing protein; B lymphocyte adapter protein BAM32; Bam32; Dual adaptor for phosphotyrosine and 3-phosphoinositides 1; PHISH; dual adapter for phosphotyrosine and 3-phosphoinositides

• Gene Name:

  DAPP1

• UniProt:

  Q9UN19

• Reactivity:

  Human, Mouse

• Tissue Specificity:

  Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR) -signaling downstream of PI3K.

• Molecular Weight:

  32194 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

• Subcellular Location:

  Cytoplasm. Membrane; Peripheral membrane protein. Membrane-associated after cell stimulation leading to its translocation.