CREB Colorimetric Cell-Based ELISA Kit

• Description:

  The CREB Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CREB protein expression profile in cells. The kit can be used for measuring the relative amounts of CREB in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CREB.

• Synonyms:

  CAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1

• Gene Name:

  CREB1

• UniProt:

  P16220

• Reactivity:

  Human, Mouse, Rat

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

• Molecular Weight:

  36688 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Cyclic AMP-responsive element-binding protein 1

• Subcellular Location:

  Nucleus.