Claudin 4 Colorimetric Cell-Based ELISA Kit

• Description:

  The Claudin 4 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Claudin 4 protein expression profile in cells. The kit can be used for measuring the relative amounts of Claudin 4 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Claudin 4.

• Synonyms:

  Claudin-4; CLD4; CLDN4; Clostridium perfringens enterotoxin receptor; CPE- receptor; CPE-R; CPER; CPETR1; WBSCR8; Williams-Beuren syndrome chromosome region 8 protein

• Gene Name:

  CLDN4CPER , CPETR1 , WBSCR8

• UniProt:

  O14493

• Reactivity:

  Human, Mouse, Rat

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

• Molecular Weight:

  22077 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Claudin-4

• Subcellular Location:

  Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. CLDN4 is required for tight junction localization in the kidney.