APLP2 Colorimetric Cell-Based ELISA Kit

• Description:

  The APLP2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor APLP2 protein expression profile in cells. The kit can be used for measuring the relative amounts of APLP2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on APLP2.

• Synonyms:

  Amyloid protein homolog; Amyloid-like protein 2 precursor; APLP2; APP2; APPH; APPL2; CDEBP; CDEI-box binding protein

• Gene Name:

  APLP2

• UniProt:

  Q06481

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3' (CDEI box) . Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity) .

• Molecular Weight:

  86956 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Amyloid-like protein 2

• Subcellular Location:

  Cell membrane; Single-pass type I membrane protein. Nucleus.