Anti-FIR FARP2 Antibody

• Background:

  Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion By similarity.
  
  Nagase T., DNA Res. 5:31-39(1998).
  The MGC Project Team, Genome Res. 14:2121-2127(2004).
  Jandrig B., Oncogene 23:9295-9302(2004).

• Description:

  Boster Bio Anti-FIR FARP2 Antibody (Catalog # A08176) . Tested in WB applications. This antibody reacts with Human, Mouse.

• Synonyms:

  FERM, RhoGEF and pleckstrin domain-containing protein 2; FERM domain including RhoGEF; FIR; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3; FARP2; KIAA0793, PLEKHC3

• Gene Name:

  FARP2

• UniProt:

  O94887

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from Internal of human FIR.

• Clonality:

  Polyclonal

• Applications:

  WB

• Field of Research:

  Axonal Guidance Proteins, G Protein Signaling, Growth and Development, Neural Signal Transduction, Neurology Process, Neuroscience, Ras Family, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Dilution:

  Western blotting: 1:500~1:3000

• Form:

  Liquid

• Function:

  Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity) . .

• Molecular Weight:

  119888 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  FERM, RhoGEF and pleckstrin domain-containing protein 2