FIR Colorimetric Cell-Based ELISA

• Description:

  The FIR Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor FIR protein expression profile in cells. The kit can be used for measuring the relative amounts of FIR in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on FIR.

• Synonyms:

  FERM, ARHGEF and pleckstrin domain-containing protein 2; FERM domain-including RhoGEF; FIR; FERM, RhoGEF and pleckstrin domain-containing protein 2; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3; FARP2; KIAA0793, PLEKHC3

• Gene Name:

  FARP2

• UniProt:

  O94887

• Reactivity:

  Human, Mouse

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity) .

• Molecular Weight:

  119888 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  FERM, ARHGEF and pleckstrin domain-containing protein 2