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Benproperine (phosphate)

CAT: 0804-HY-114657A-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114657A-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Benproperine phosphate is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate has the potential for a cough suppressant and suppresses cancer cell migration and tumor metastasis[1].
CAS Number
19428-14-9
Product Name Alternative
1-O-hexyl-2,3,5-trimethylhydroquinone; HX-1171; BTT-105, YL0919
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Arp2/3 Complex
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/benproperine-phosphate.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
CC(N1CCCCC1)COC2=CC=CC=C2CC3=CC=CC=C3.O=P(O)(O)O
Molecular Formula
C21H30NO5P
Molecular Weight
407.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Yae Jin Yoon, et al. Benproperine, an ARPC2 inhibitor, suppresses cancer cell migration and tumor metastasis. Biochem Pharmacol. 2019 May;163:46-59.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched

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