SR33805 (oxalate)

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SR33805 (oxalate)

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804-HY-103313

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SR33805 (oxalate)

CAS Number: 121346-33-6
UNSPSC Description: SR33805 oxalate is a potent Ca2+ channel antagonist, with EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively. SR33805 oxalate blocks L-type but not T-type Ca2+ channels. SR33805 oxalate can be used for the research of acute or chronic failing hearts[1][2].
Target Antigen: Calcium Channel
Type: Reference compound
Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
Applications: Neuroscience-Neuromodulation
Field of Research: Cardiovascular Disease
Assay Protocol: https://www.medchemexpress.com/sr33805-oxalate.html
Smiles: O=S(C1=CC=C(OCCCN(C)CCC2=CC=C(OC)C(OC)=C2)C=C1)(C(N3C)=C(C(C)C)C4=C3C=CC=C4)=O.O=C(O)C(O)=O
Molecular Weight: 654.77
References & Citations: [1]Romey G, et, al. Effects of two chemically related new Ca2+ channel antagonists, SR33557 (fantofarone) and SR33805, on the L-type cardiac channel. Eur J Pharmacol. 1994 Sep 22; 263(1-2): 101-5.|[2]Mou YA, et, al. Beneficial effects of SR33805 in failing myocardium. Cardiovasc Res. 2011 Aug 1; 91(3): 412-9.|[3]Hainaud P, et, al. The calcium inhibitor SR33805 reduces intimal formation following injury of the porcine carotid artery. Atherosclerosis. 2001 Feb 1; 154(2): 301-8.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Complementary Product Range

Our range of products, including SR33805 (oxalate), falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

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Cat	Name
HY-103313	SR33805 (oxalate)
HY-136909-05	SR33805
HY-136909-04	SR33805
HY-136909-06	SR33805
HY-136909-03	SR33805
HY-136909-02	SR33805
HY-136909-01	SR33805
HY-121701	SR33805 (analog)
HY-111081C	(±)-PPCC (oxalate)
HY-107656	PTAC (oxalate)