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Gp100 (619-627)

CAT: 0804-HY-P1796Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P1796Size:1 Each
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Description
Gp100 (619-627) is amino acids 619 to 627 fragment of human melanoma antigen glycoprotein 100 (gp100) . Gp100 has been a widely studied target for melanoma immunotherapy[1].
CAS Number
187987-68-4
UNSPSC
12352209
Target
Others
Type
Peptides
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gp100-619-627.html
Solubility
H2O
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Molecular Formula
C49H82N14O14S
Molecular Weight
1123.33
References & Citations
[1]Bianchi V, et al. A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen. J Biol Chem. 2016 Apr 22;291 (17) :8951-9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

Chemical Information

H-Arg-Leu-Met-Lys-Gln-Asp-Phe-Ser-Val-OH
CAS Number187987-68-4
PubChem CID44345772
IUPAC Name(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylbutanoic acid
Molecular FormulaC49H82N14O14S
Molecular Weight1123.3
XLogP-7.3
Topological Polar Surface Area512
Hydrogen Bond Donor Count16
Hydrogen Bond Acceptor Count18
Rotatable Bond Count39
Heavy Atom Count78
Formal Charge0
Complexity2020
SMILES
CC(C)C[C@@H](C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)N
InChI
InChI=1S/C49H82N14O14S/c1-26(2)22-33(59-40(68)29(51)14-11-20-55-49(53)54)44(72)58-32(18-21-78-5)43(71)56-30(15-9-10-19-50)41(69)57-31(16-17-37(52)65)42(70)61-35(24-38(66)67)46(74)60-34(23-28-12-7-6-8-13-28)45(73)62-36(25-64)47(75)63-39(27(3)4)48(76)77/h6-8,12-13,26-27,29-36,39,64H,9-11,14-25,50-51H2,1-5H3,(H2,52,65)(H,56,71)(H,57,69)(H,58,72)(H,59,68)(H,60,74)(H,61,70)(H,62,73)(H,63,75)(H,66,67)(H,76,77)(H4,53,54,55)/t29-,30-,31-,32-,33-,34-,35-,36-,39-/m0/s1
InChIKey
LFNCWQRPXOCXHL-SJPMHHPLSA-N
Chemical Structure
2D Structure
2D structure of H-Arg-Leu-Met-Lys-Gln-Asp-Phe-Ser-Val-OH
CAS: 187987-68-4
CID: 44345772
Formula: C49H82N14O14S
MW: 1123.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1123.3
XLogP3-7.3
Hydrogen Bond Donor Count16
Hydrogen Bond Acceptor Count18
Rotatable Bond Count39
Exact Mass1122.58556452
Monoisotopic Mass1122.58556452
Topological Polar Surface Area512 Ų
Heavy Atom Count78
Formal Charge0
Complexity2020
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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