αVβ8-IN-1

CAT: 0804-HY-164360-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-164360-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

αVβ8-IN-1 is a αVβ8 integrin inhibitor. αVβ8-IN-1 has been shown to inhibit the growth of tumors such as EMT6, CT26, KPC, and TKCC-10. αVβ8-IN-1 can be used in research related to idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonia (NSIP), and tumors[1].

CAS Number

3048440-55-4

UNSPSC

12352005

Target

Integrin

Type

Reference compound

Related Pathways

Cytoskeleton

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/αvβ8-in-1.html

Purity

96.31

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC([C@H](CCOCCCCC(N1)=CC=C2C1=NCCC2)NC(C3(C4=C(Cl)N=CN=C4C)CC3)=O)=O

Molecular Formula

C25H32ClN5O4

Molecular Weight

502.01

References & Citations

[1]Machajewski, timothy D, et al. alpha-v-beta-8 integrin inhibitors and uses thereof. US2023/085812. 2024.07.04.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Alternative Products

Catalog	Name
BUP22983-01	αVβ8-IN-1
sc-130337	PRX V (8)
ANT-14661-50ug	TCR V β 8.1 / 8.2 Monoclonal Antibody
E55A06421	Mouse TCR V β 8.1/8.2 Antibody
sc-33648	TCR V β 8.1-3 (F23.1)
sc-33648 PE	TCR V β 8.1-3 PE
sc-73130	TCR V β 8.1-2 (3H2987)
sc-33648 FITC	TCR V β 8.1-3 FITC
sc-59387	TCR V β 8.1-2 (KJ16)
GT04353	PE anti-mouse TCR Vβ8.1, 8.2

αVβ8-IN-1

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