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FG 488 DHPE

CAT: 0804-HY-D1560Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-D1560Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm.FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well[1][2].
CAS Number
438476-80-3
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/fg-488-dhpe.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2(C3=CC(F)=C(O)C=C3OC4=CC(O)=C(F)C=C42)C5=CC=C(C(NCCOP(OC[C@@H](COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCC)=O)(O)=O)=O)C=C51
Molecular Formula
C58H82F2NO14P
Molecular Weight
1086.24
References & Citations
[1]Schwamborn M, et al. Monitoring ATPase induced pH changes in single proteoliposomes with the lipid-coupled fluorophore Oregon Green 488. Analyst. 2017 Jul 10;142 (14) :2670-2677. |[2]Gerdes B, et al. Quantification of Hv1-induced proton translocation by a lipid-coupled Oregon Green 488-based assay. Anal Bioanal Chem. 2018 Oct;410 (25) :6497-6505.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

Chemical Information

FG 488 Dhpe
CAS Number438476-80-3
PubChem CID165412492
IUPAC Name[(2R)-3-[2-[(2',7'-difluoro-3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carbonyl)amino]ethoxy-hydroxyphosphoryl]oxy-2-hexadecanoyloxypropyl] hexadecanoate
Molecular FormulaC58H82F2NO14P
Molecular Weight1086.2
XLogP16.2
Topological Polar Surface Area213
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count16
Rotatable Bond Count41
Heavy Atom Count76
Formal Charge0
Complexity1720
SMILES
CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCNC(=O)C1=CC2=C(C=C1)C3(C4=CC(=C(C=C4OC5=CC(=C(C=C53)F)O)O)F)OC2=O)OC(=O)CCCCCCCCCCCCCCC
InChI
InChI=1S/C58H82F2NO14P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-54(64)70-40-43(73-55(65)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)41-72-76(68,69)71-34-33-61-56(66)42-31-32-45-44(35-42)57(67)75-58(45)46-36-48(59)50(62)38-52(46)74-53-39-51(63)49(60)37-47(53)58/h31-32,35-39,43,62-63H,3-30,33-34,40-41H2,1-2H3,(H,61,66)(H,68,69)/t43-/m1/s1
InChIKey
IXJDCQVYVRWFPD-VZUYHUTRSA-N
Chemical Structure
2D Structure
2D structure of FG 488 Dhpe
CAS: 438476-80-3
CID: 165412492
Formula: C58H82F2NO14P
MW: 1086.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1086.2
XLogP316.2
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count16
Rotatable Bond Count41
Exact Mass1085.54409961
Monoisotopic Mass1085.54409961
Topological Polar Surface Area213 Ų
Heavy Atom Count76
Formal Charge0
Complexity1720
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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